SAMe & TMG natural lemon

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  • Supports Biochemical Reactions Requiring Methyl Groups†
  • Supports Neurotransmitter Synthesis and Healthy Mood†
  • Facilitates Conversion of Homocysteine to Glutathione†
  • Supports Liver Health and Function†
  • Promotes Joint Comfort†

ID #
SAMe & TMG natural lemon
TOTAL (Shipping & Tax not included)

SAMe & TMG is a sweet, yet slightly tart lemon-flavored powder. SAMe (S-adenosyl-L-methionine) and TMG (trimethylglycine) are naturally occurring substances that act as methyl donors during vital biochemical processes in the body. Methylation is essential to normal cell health and function. It can decline with age or chronic alcohol consumption, and it can be limited in some individuals due to their genetic makeup.†

SAMe donates methyl groups, which are needed for the synthesis of neurotransmitters, proteins, nucleic acids, and phospholipids. It supports glutathione production, liver health, joint comfort, and a healthy mood. TMG is an especially important methyl donor involved in the metabolism of homocysteine and the formation of SAMe. TMG ultimately supports cardiovascular and neurological health, as well as normal cell-life regulation.†

XYMOGEN’s SAMe & TMG formulation contains a minimum of 70% of the SS isomer of SAMe, the active form the body can use most readily. This concentration makes SAMe & TMG cost effective as most SAMe formulations on the market contain less than 44% active SS isomer. Nitrogen-purged foil sachets maximize stability.

Consume one sachet one to four times daily away from meals, or as directed by your healthcare practitioner. Preferably pour a small amount of the contents of a sachet directly into the mouth and allow contents to dissolve. Then repeat process until contents of the entire sachet have dissolved in the mouth. Alternatively, contents may be added to 2-4 oz of water or preferred liquid; stir and drink within 15 minutes.

Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Use special caution in individuals with bipolar disorder. Do not use if tamper seal is damaged.

Keep closed in a cool, dry place out of reach of children.

Supplement Facts

Serving Size 1 Sachet (2.9 g)
Servings Per Container 30

Amount Per Serving % Daily Value
S-adenosyl-L-methionine 400 mg *
Betaine Anhydrous (trimethylglycine) 600 mg *

* Daily Value not established

OTHER INGREDIENTS: Sorbitol, calcium carbonate, citric acid, malic acid, stearic acid, calcium choloride, calcium oxide, turmeric extract (natural color), silica, and natural lemon flavor.

DOES NOT CONTAIN: Wheat, gluten, corn protein, yeast, soy, animal or dairy products, fish, shellfish, egg, artificial colors, artificial sweeteners, or preservatives.

European Patent # EP2189154A1

LEGAL NOTICE: XYMOGEN's Exclusive Professional Formulas are available through select licensed health care professionals. The Internet Sale and Discounting of XYMOGEN formulas are strictly prohibited. makes XYMOGEN formulas available only to patients of our clinic. If you are a patient of NaturoMedica, you may inquire about XYMOGEN by calling 1-888-4NATURO or emailing

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Although we try to keep product information up-to-date and error-free, sometimes formulation changes may occur without notice. Please read all product labels carefully to confirm ingredients, warnings, and dosage before using any supplements. If you ever receive a product which differs from what is represented, please let us know and we'll be happy to make it right.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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