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Contains a blend of ingredients shown to improve mood and reduce stress†

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Key ingredients

Taurine: Neuroprotective amino acid that provides antioxidant protection and demonstrates GABA-A agonist activity (1-3). GABA is the primary inhibitory neurotransmitter in the brain important for calm and sleep (4-6).

L-theanine: Amino acid that acts as a glutamate receptor antagonist (7)†. In a randomized, double-blind, placebo-controlled study, L-theanine was shown to significantly reduce stress (8)†.

5-HTP (from Griffonia simplicifolia seed extract): 5-hydroxytryptophan (5-HTP) crosses the blood-brain barrier and is a precursor to serotonin and melatonin (9). Serotonin is important for regulating mood and sleep-wake function (10). In a randomized, double-blind study, 5-HTP was shown to significantly improve mood (11).

Vitamins B and C: Active forms of vitamin B6, folate, B12, and C are important for serotonin synthesis (12-16).

1. Kumari N, et al. Adv Exp Med Biol. 2013;775:19-27.
2. Shimada K, et al. Adv Exp Med Biol. 2015;803:581-96.
3. Kletke O, et al. PLoS One. 2013;8(4):e61733.
4. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
5. Mohler H. Neuropharmacology. 2012;62(1):42-53.
6. Saper C, et al. Nature. 2005;437(7063):1257-63.
7. Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683-2686.
8. Kimura K, et al. Biol Psychol. 2007; 74(1):39-45.
9. Shaw K, et al. Cochrane Database Syst Rev. 2002;(1):CD003198.
10. Monti J. Sleep Med Rev. 2011;15(4):269-81.
11. Jangid P, et al. Asian J Psychiatr. 2013;6(1):29-34.
12. Dakshinamurti K, et al. Ann N Y Acad Sci. 1990;585:128-44.
13. Bottiglieri T. Psychiatr Clin North Am. 2013;36(1):1-13.
14. Stahl S. J Clin Psychiatry. 2008;69(9):1352-3.
15. Antoniades C, et al. Circulation. 2006;114(11):1193-201.
16. May J, et al. Brain Res Bull. 2013;90:35-42.

Take 1-3 capsules one to two times daily or as directed by your healthcare provider

If you are pregnant or nursing, consult your healthcare provider before use.

Supplement Facts

Serving Size: 3 Capsules
Servings Per Container: 40

Amount Per Serving % Daily Value
Vitamin C (as ascorbic acid) 40 mg 67%
Vitamin B6 (as pyridoxal 5'-phosphate) 9 mg 450%
Folate (from (6S)-5-methyltetra-hydrofolic acid, glucosamine salt‡) 200 mcg 50%
Vitamin B12 (as methylcobalamin) 30 mcg 500%
Magnesium (as magnesium bisglycinate chelate) 50 mg 13%
Zinc (as zinc bisglycinate chelate) 10 mg 67%
Selenium (as L-selenomethionine) 70 mcg 100%
Proprietary Blend: 950 mg **
Taurine, L-theanine, 5-hydroxytryptophan (from Griffonia simplicifolia seed extract)

** Daily Value not established.

OTHER INGREDIENTS: Vegetable capsule (Hypromellose, water), Microcrystalline cellulose, and Magnesium stearate (vegetable source).

‡ This product uses Gnosis S.p.A's (6S)-5-methyltetrahydrofolic acid, glucosamine salt (Quatrefolic®) and is protected by U.S. Patent No. 7,947,662. Quatrefolic is a registered trademark of Gnosis S.p.A., Milan, Italy.

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Although we try to keep product information up-to-date and error-free, sometimes formulation changes may occur without notice. Please read all product labels carefully to confirm ingredients, warnings, and dosage before using any supplements. If you ever receive a product which differs from what is represented, please let us know and we'll be happy to make it right.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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